Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer

Estrogens have been shown to elicit anticancer effects against estrogen receptor α (ER)‐positive breast cancer. We sought to determine the mechanism underlying the therapeutic response. Response to 17β‐estradiol was assessed in ER+ breast cancer models with resistance to estrogen deprivation: WHIM16...

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Pubblicato in:Mol Oncol
Autori principali: Hosford, Sarah R., Shee, Kevin, Wells, Jason D., Traphagen, Nicole A., Fields, Jennifer L., Hampsch, Riley A., Kettenbach, Arminja N., Demidenko, Eugene, Miller, Todd W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670014/
https://ncbi.nlm.nih.gov/pubmed/31180176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12528
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