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Macrocyclic Inhibitors of Hsp90

Heat shock proteins (HSP) are a family of highly conserved proteins, whose expression increases in response to stresses that may threaten cell survival. Over the past decade, heat shock protein 90 (Hsp90) has emerged as a potential therapeutic target for cancer as it plays a vital role in normal cel...

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Bibliografiska uppgifter
Huvudupphovsmän: Johnson, Victoria A., Singh, Erinprit K., Nazarova, Lidia A., Alexander, Leslie D., McAlpine, Shelli R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105290/
https://ncbi.nlm.nih.gov/pubmed/20536417
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