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Macrocyclic Inhibitors of Hsp90

Heat shock proteins (HSP) are a family of highly conserved proteins, whose expression increases in response to stresses that may threaten cell survival. Over the past decade, heat shock protein 90 (Hsp90) has emerged as a potential therapeutic target for cancer as it plays a vital role in normal cel...

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Detalhes bibliográficos
Main Authors: Johnson, Victoria A., Singh, Erinprit K., Nazarova, Lidia A., Alexander, Leslie D., McAlpine, Shelli R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105290/
https://ncbi.nlm.nih.gov/pubmed/20536417
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