Nalaganje...
Inhibition of hedgehog signaling by stereochemically defined des-triazole itraconazole analogues
Dysregulation of the hedgehog (Hh) signaling pathway is associated with cancer occurrence and development in various malignancies. Previous structure-activity relationships (SAR) studies have provided potent Itraconazole (ITZ) analogues as Hh pathway antagonists. To further expand on our SAR for the...
Shranjeno v:
| izdano v: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942223/ https://ncbi.nlm.nih.gov/pubmed/31761657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.126794 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|