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Formulation and evaluation of itraconazole liposomes for hedgehog pathway inhibition

Itraconazole (ITZ) is an FDA-approved antifungal agent that has recently been explored for novel biological properties. In particular, ITZ was identified as a potent inhibitor of the hedgehog (Hh) pathway, a cell signalling pathway that has been linked to a variety of cancers and accounts for ~ 25 %...

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Pubblicato in:J Liposome Res
Autori principali: Pace, Jennifer R., Jog, Rajan, Burgess, Diane J., Hadden, M. Kyle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113120/
https://ncbi.nlm.nih.gov/pubmed/31576768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08982104.2019.1668011
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