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In vivo elongation of thin filaments results in heart failure
A novel cardiac-specific transgenic mouse model was generated to identify the physiological consequences of elongated thin filaments during post-natal development in the heart. Remarkably, increasing the expression levels in vivo of just one sarcomeric protein, Lmod2, results in ~10% longer thin fil...
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| 發表在: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941805/ https://ncbi.nlm.nih.gov/pubmed/31899774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226138 |
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