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Nebulin Interacts with CapZ and Regulates Thin Filament Architecture within the Z-Disc

The barbed ends of actin filaments in striated muscle are anchored within the Z-disc and capped by CapZ; this protein blocks actin polymerization and depolymerization in vitro. The mature lengths of the thin filaments are likely specified by the giant “molecular ruler” nebulin, which spans the lengt...

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Detalles Bibliográficos
Main Authors: Pappas, Christopher T., Bhattacharya, Nandini, Cooper, John A., Gregorio, Carol C.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366866/
https://ncbi.nlm.nih.gov/pubmed/18272787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0690
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