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Nebulin Interacts with CapZ and Regulates Thin Filament Architecture within the Z-Disc
The barbed ends of actin filaments in striated muscle are anchored within the Z-disc and capped by CapZ; this protein blocks actin polymerization and depolymerization in vitro. The mature lengths of the thin filaments are likely specified by the giant “molecular ruler” nebulin, which spans the lengt...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366866/ https://ncbi.nlm.nih.gov/pubmed/18272787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0690 |
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