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Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality
Leiomodin 2 (Lmod2) is an actin-binding protein that has been implicated in the regulation of striated muscle thin filament assembly; its physiological function has yet to be studied. We found that knockout of Lmod2 in mice results in abnormally short thin filaments in the heart. We also discovered...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640780/ https://ncbi.nlm.nih.gov/pubmed/26487682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508273112 |
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