Carregant...

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality

Leiomodin 2 (Lmod2) is an actin-binding protein that has been implicated in the regulation of striated muscle thin filament assembly; its physiological function has yet to be studied. We found that knockout of Lmod2 in mice results in abnormally short thin filaments in the heart. We also discovered...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pappas, Christopher T., Mayfield, Rachel M., Henderson, Christine, Jamilpour, Nima, Cover, Cathleen, Hernandez, Zachary, Hutchinson, Kirk R., Chu, Miensheng, Nam, Ki-Hwan, Valdez, Jose M., Wong, Pak Kin, Granzier, Henk L., Gregorio, Carol C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640780/
https://ncbi.nlm.nih.gov/pubmed/26487682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508273112
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!