Small Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

Small molecules that directly target MYC and are also well tolerated in vivo will provide invaluable chemical probes and potential anti-cancer therapeutic agents. We developed a series of small molecule MYC inhibitors that engage MYC inside cells, disrupt MYC/MAX dimers, and impair MYC-driven gene e...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cancer Cell
Hoofdauteurs: Han, Huiying, Jain, Atul D., Truica, Mihai I., Izquierdo-Ferrer, Javier, Anker, Jonathan F., Lysy, Barbara, Sagar, Vinay, Luan, Yi, Chalmers, Zachary R., Kenji Unno, Mok, Hanlin, Vatapalli, Rajita, Yoo, Young A, Rodriguez, Yara, Kandela, Irawati, Parker, J. Brandon, Chakravarti, Debabrata, Mishra, Rama K., Schiltz, Gary E., Abdulkadir, Sarki A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939458/
https://ncbi.nlm.nih.gov/pubmed/31679823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.10.001
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items