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Turning up the Heat on MYC: progress in small molecule inhibitors
MYC is a highly validated oncogenic transcription factor and cancer target. However, the disordered nature of this protein has made it a challenging target, with no clinical stage, direct small molecule MYC inhibitors available. Recent work leveraging a large in silico chemical library and a rapid i...
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| 出版年: | Cancer Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855142/ https://ncbi.nlm.nih.gov/pubmed/33087323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-2959 |
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