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Turning up the Heat on MYC: progress in small molecule inhibitors
MYC is a highly validated oncogenic transcription factor and cancer target. However, the disordered nature of this protein has made it a challenging target, with no clinical stage, direct small molecule MYC inhibitors available. Recent work leveraging a large in silico chemical library and a rapid i...
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| Publicado no: | Cancer Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855142/ https://ncbi.nlm.nih.gov/pubmed/33087323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-2959 |
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