Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile

Non-alcoholic fatty liver disease (NAFLD) culminates in insulin resistance and metabolic syndrome. Because there are no approved pharmacological treatment agents for non-alcoholic steatohepatitis (NASH) and NAFLD, different signaling pathways are under investigation for drug development with the foc...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Huang, Kai-Wen, Reebye, Vikash, Czysz, Katherine, Ciriello, Simona, Dorman, Stephanie, Reccia, Isabella, Lai, Hong-Shiee, Peng, Ling, Kostomitsopoulos, Nikos, Nicholls, Joanna, Habib, Robert S., Tomalia, Donald A., Sætrom, Pål, Wilkes, Edmund, Cutillas, Pedro, Rossi, John J., Habib, Nagy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938799/
https://ncbi.nlm.nih.gov/pubmed/31877412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.044
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