Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo

The 5-year survival rate for pancreatic ductal adenocarcinoma (PDAC) remains dismal despite current chemotherapeutic agents and inhibitors of molecular targets. As the incidence of PDAC constantly increases, more effective multidrug approaches must be made. Here, we report a novel method of deliveri...

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Publicado en:Mol Ther
Autores principales: Yoon, Sorah, Huang, Kai-Wen, Reebye, Vikash, Mintz, Paul, Tien, Yu-Wen, Lai, Hong-Shiee, Sætrom, Pål, Reccia, Isabella, Swiderski, Piotr, Armstrong, Brian, Jozwiak, Agnieszka, Spalding, Duncan, Jiao, Long, Habib, Nagy, Rossi, John J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923325/
https://ncbi.nlm.nih.gov/pubmed/26983359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.60
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