Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo

The 5-year survival rate for pancreatic ductal adenocarcinoma (PDAC) remains dismal despite current chemotherapeutic agents and inhibitors of molecular targets. As the incidence of PDAC constantly increases, more effective multidrug approaches must be made. Here, we report a novel method of deliveri...

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Publicat a:Mol Ther
Autors principals: Yoon, Sorah, Huang, Kai-Wen, Reebye, Vikash, Mintz, Paul, Tien, Yu-Wen, Lai, Hong-Shiee, Sætrom, Pål, Reccia, Isabella, Swiderski, Piotr, Armstrong, Brian, Jozwiak, Agnieszka, Spalding, Duncan, Jiao, Long, Habib, Nagy, Rossi, John J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923325/
https://ncbi.nlm.nih.gov/pubmed/26983359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.60
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