Translational Prospects and Challenges in Human Induced Pluripotent Stem Cell Research in Drug Discovery

Por Hosoya, Masaki, Czysz, Katherine
Publicado no Cells (2016)

DMSO Efficiently Down Regulates Pluripotency Genes in Human Embryonic Stem Cells during Definitive Endoderm Derivation and Increases the Proficiency of Hepatic Differentiation

Por Czysz, Katherine, Minger, Stephen, Thomas, Nick
Publicado no PLoS One (2015)

iPSC-derived hepatocytes generated from NASH donors provide a valuable platform for disease modeling and drug discovery

Por Gurevich, Igor, Burton, Sarah A., Munn, Christie, Ohshima, Makiko, Goedland, Madelyn E., Czysz, Katherine, Rajesh, Deepika
Publicado no Biol Open (2020)

Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile

Por Huang, Kai-Wen, Reebye, Vikash, Czysz, Katherine, Ciriello, Simona, Dorman, Stephanie, Reccia, Isabella, Lai, Hong-Shiee, Peng, Ling, Kostomitsopoulos, Nikos, Nicholls, Joanna, Habib, Robert S., Tomalia, Donald A., Sætrom, Pål, Wilkes, Edmund, Cutillas, Pedro, Rossi, John J., Habib, Nagy A.
Publicado no Mol Ther Nucleic Acids (2019)