A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells

Upon functional loss of insulin producing islet β-cells, some patients with diabetes become dependent on life-long insulin supplementation therapy. Bioengineering surrogate insulin producing cells is an alternative replacement strategy. We have developed a novel approach using short-activating RNA o...

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Detalhes bibliográficos
Main Authors: Reebye, Vikash, Sætrom, Pål, Mintz, Paul J, Rossi, John J, Kasahara, Noriyuki, Nteliopoulos, Georgios, Nicholls, Joanna, Haoudi, Abdelali, Gordon, Myrtle, Habib, Nagy A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696904/
https://ncbi.nlm.nih.gov/pubmed/23736775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.23
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