Loss of MafA and MafB expression promotes islet inflammation

Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf transcription factors induced autoimmune processes in...

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Published in:Sci Rep
Main Authors: Singh, Tania, Colberg, Jesper K., Sarmiento, Luis, Chaves, Patricia, Hansen, Lisbeth, Bsharat, Sara, Cataldo, Luis R., Dudenhöffer-Pfeifer, Monika, Fex, Malin, Bryder, David, Holmberg, Dan, Sitnicka, Ewa, Cilio, Corrado, Prasad, Rashmi B., Artner, Isabella
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591483/
https://ncbi.nlm.nih.gov/pubmed/31235823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45528-x
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