Targeting PDZ Binding Kinase Is Anti-tumorigenic in Novel Preclinical Models of ACC

Adrenocortical carcinoma (ACC) is an aggressive orphan malignancy with less than 35% 5-year survival and 75% recurrence. Surgery remains the primary therapy and Mitotane, an adrenolytic, is the only FDA approved drug with wide range toxicities and poor tolerability. There are no targeted agents avai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Kar, Adwitiya, Zhang, Yu, Yacob, Betelehem W., Saeed, Jordan, Tompkins, Kenneth D., Bagby, Stacey M., Pitts, Todd M., Somerset, Hilary, Leong, Stephen, Wierman, Margaret E., Kiseljak-Vassiliades, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938568/
https://ncbi.nlm.nih.gov/pubmed/31325906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0262
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados