Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment

CONTEXT: Although the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research models to study immunotherapy in adrenocortical carcinoma (ACC) are lacking. OBJECTIVE: To explore the effect of anti-PD1 immunotherapy on the alteration of...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Lang, Julie, Capasso, Anna, Jordan, Kimberly R, French, Jena D, Kar, Adwitiya, Bagby, Stacey M, Barbee, Jacob, Yacob, Betelehem W, Head, Lia S, Tompkins, Kenneth D, Freed, Brian M, Somerset, Hilary, Clark, Toshimasa J, Pitts, Todd M, Messersmith, Wells A, Eckhardt, S Gail, Wierman, Margaret E, Leong, Stephen, Kiseljak-Vassiliades, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947837/
https://ncbi.nlm.nih.gov/pubmed/31513709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz014
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