Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment

CONTEXT: Although the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research models to study immunotherapy in adrenocortical carcinoma (ACC) are lacking. OBJECTIVE: To explore the effect of anti-PD1 immunotherapy on the alteration of...

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Bibliografische gegevens
Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: Lang, Julie, Capasso, Anna, Jordan, Kimberly R, French, Jena D, Kar, Adwitiya, Bagby, Stacey M, Barbee, Jacob, Yacob, Betelehem W, Head, Lia S, Tompkins, Kenneth D, Freed, Brian M, Somerset, Hilary, Clark, Toshimasa J, Pitts, Todd M, Messersmith, Wells A, Eckhardt, S Gail, Wierman, Margaret E, Leong, Stephen, Kiseljak-Vassiliades, Katja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Clinical Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947837/
https://ncbi.nlm.nih.gov/pubmed/31513709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz014
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