Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment

CONTEXT: Although the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research models to study immunotherapy in adrenocortical carcinoma (ACC) are lacking. OBJECTIVE: To explore the effect of anti-PD1 immunotherapy on the alteration of...

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Dettagli Bibliografici
Pubblicato in:J Clin Endocrinol Metab
Autori principali: Lang, Julie, Capasso, Anna, Jordan, Kimberly R, French, Jena D, Kar, Adwitiya, Bagby, Stacey M, Barbee, Jacob, Yacob, Betelehem W, Head, Lia S, Tompkins, Kenneth D, Freed, Brian M, Somerset, Hilary, Clark, Toshimasa J, Pitts, Todd M, Messersmith, Wells A, Eckhardt, S Gail, Wierman, Margaret E, Leong, Stephen, Kiseljak-Vassiliades, Katja
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Clinical Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947837/
https://ncbi.nlm.nih.gov/pubmed/31513709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz014
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