SAT-LB064 Mitotane Induces Autophagy: A Mechanism to Promote Chemoresistance in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is an orphan malignancy with dismal survival rates. Although recent large genomic studies have shed insight into underlying molecular mechanisms, there are currently no targeted therapies available. Autophagy is an important cellular process to promote survival in a lo...

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Bibliographische Detailangaben
Veröffentlicht in:J Endocr Soc
Hauptverfasser: Tompkins, Kenneth, Towers, Christina, Kar, Adwitiya, Zhang, Yu, Kiseljak-Vassiliades, Katja, Thorburn, Andrew, Wierman, Margaret
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Adrenal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551990/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-LB064
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