SAT-LB064 Mitotane Induces Autophagy: A Mechanism to Promote Chemoresistance in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is an orphan malignancy with dismal survival rates. Although recent large genomic studies have shed insight into underlying molecular mechanisms, there are currently no targeted therapies available. Autophagy is an important cellular process to promote survival in a lo...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Main Authors: Tompkins, Kenneth, Towers, Christina, Kar, Adwitiya, Zhang, Yu, Kiseljak-Vassiliades, Katja, Thorburn, Andrew, Wierman, Margaret
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2019
Assuntos:
Adrenal
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551990/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-LB064
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