Monophosphoryl Lipid A Attenuates Multiorgan Dysfunction during Post-burn Pseudomonas aeruginosa Pneumonia in Sheep

BACKGROUND: Monophosphoryl lipid A (MPLA) is a TLR4 agonist that has potent immunomodulatory properties and modulates innate immune function to improve host resistance to infection with common nosocomial pathogens in mice. The goal of this study was to assess the safety and efficacy of MPLA in a she...

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Publicat a:Shock
Autors principals: Fukuda, Satoshi, Ihara, Koji, Bohannon, Julia K., Hernandez, Antonio, Patil, Naeem K., Luan, Liming, Stothers, Cody, Stark, Ryan, Prough, Donald S., Herndon, David N., Sherwood, Edward R., Enkhbaatar, Perenlei
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937402/
https://ncbi.nlm.nih.gov/pubmed/31045990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001364
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