Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A

Monophosphoryl lipid A (MPLA), a less toxic derivative of lipopolysaccharide (LPS), is employed as a vaccine adjuvant and is under investigation as a non-specific immunomodulator. However, the differential response of human leukocytes to MPLA and LPS has not been well characterized. The goal of this...

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Publicado en:Sci Rep
Main Authors: Luan, Liming, Patil, Naeem K., Guo, Yin, Hernandez, Antonio, Bohannon, Julia K., Fensterheim, Benjamin A., Wang, Jingbin, Xu, Yaomin, Enkhbaatar, Perenlei, Stark, Ryan, Sherwood, Edward R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215261/
https://ncbi.nlm.nih.gov/pubmed/28053314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40050
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