Monophosphoryl Lipid A Attenuates Multiorgan Dysfunction during Post-burn Pseudomonas aeruginosa Pneumonia in Sheep

BACKGROUND: Monophosphoryl lipid A (MPLA) is a TLR4 agonist that has potent immunomodulatory properties and modulates innate immune function to improve host resistance to infection with common nosocomial pathogens in mice. The goal of this study was to assess the safety and efficacy of MPLA in a she...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Shock
Prif Awduron: Fukuda, Satoshi, Ihara, Koji, Bohannon, Julia K., Hernandez, Antonio, Patil, Naeem K., Luan, Liming, Stothers, Cody, Stark, Ryan, Prough, Donald S., Herndon, David N., Sherwood, Edward R., Enkhbaatar, Perenlei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937402/
https://ncbi.nlm.nih.gov/pubmed/31045990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001364
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