IL-15 Superagonist Expands mCD8(+ )T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection

BACKGROUND: Severely burned patients are highly susceptible to opportunistic infections and sepsis, owing to the loss of the protective skin barrier and immunological dysfunction. Interleukin-15 (IL-15) belongs to the IL-2 family of common gamma chain cytokines and stimulates the proliferation and a...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Patil, Naeem K., Luan, Liming, Bohannon, Julia K., Guo, Yin, Hernandez, Antonio, Fensterheim, Benjamin, Sherwood, Edward R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747596/
https://ncbi.nlm.nih.gov/pubmed/26859674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148452
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