The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes

Treatment with the TLR4 agonist MPLA augments innate resistance to common bacterial pathogens. However, the cellular and molecular mechanisms by which MPLA augments innate immunocyte functions are not well characterized. This study examined the importance of MyD88- and TRIF-dependent signaling for l...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Hernandez, Antonio, Bohannon, Julia K., Luan, Liming, Fensterheim, Benjamin A., Guo, Yin, Patil, Naeem K., McAdams, Chase, Wang, Jingbin, Sherwood, Edward R.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2016
Subjects:
Cell Development, Differentiation, & Trafficking
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109999/
https://ncbi.nlm.nih.gov/pubmed/27354411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1A0216-072R
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