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Therapeutic Targeting of RAS: New Hope for Drugging the “Undruggable”
RAS is the most frequently mutated oncogene in cancer and a critical driver of oncogenesis. Therapeutic targeting of RAS has been a goal of cancer research for more than 30 years due to its essential role in tumor formation and maintenance. Yet the quest to inhibit this challenging foe has been elus...
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| Veröffentlicht in: | Biochim Biophys Acta Mol Cell Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6937383/ https://ncbi.nlm.nih.gov/pubmed/31678118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2019.118570 |
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