Cargando...

RAS-targeted therapies: is the undruggable drugged?

RAS (KRAS, NRAS and HRAS) is the most frequently mutated gene family in cancers, and, consequently, investigators have sought an effective RAS inhibitor for more than three decades. Even 10 years ago, RAS inhibitors were so elusive that RAS was termed ‘undruggable’. Now, with the success of allele-s...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nat Rev Drug Discov
Autores principales: Moore, Amanda R., Rosenberg, Scott C., McCormick, Frank, Malek, Shiva
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809886/
https://ncbi.nlm.nih.gov/pubmed/32528145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-0068-6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!