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Signal Transduction by Ras-Like GTPases: A Potential Target for Anticancer Drugs

Members of the ras family of GTPases are involved in a wide variety of cellular processes including cell proliferation, differentiation, apoptosis, and transformation. The ras oncogene is one of the most frequently mutated genes in human cancer. In addition, other oncogene and tumor suppressor gene...

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Bibliographic Details
Published in:Gene Expr
Main Authors: Spaargaren, Marcel, Bischoff, James R., McCormick, Frank
Format: Artigo
Language:Inglês
Published: Cognizant Communication Corporation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134362/
https://ncbi.nlm.nih.gov/pubmed/7549466
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