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SPRED proteins and their roles in signal transduction, development, and malignancy
The roles of SPRED proteins in signaling, development, and cancer are becoming increasingly recognized. SPRED proteins comprise an N-terminal EVH-1 domain, a central c-Kit-binding domain, and C-terminal SROUTY domain. They negatively regulate signaling from tyrosine kinases to the Ras–MAPK pathway....
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| 發表在: | Genes Dev |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608746/ https://ncbi.nlm.nih.gov/pubmed/33872193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.341222.120 |
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