Signal Transduction by Ras-Like GTPases: A Potential Target for Anticancer Drugs

Por Spaargaren, Marcel, Bischoff, James R., McCormick, Frank
Publicado no Gene Expr (2018)

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

Por Toledo, Luis I., Murga, Matilde, Zur, Rafal, Soria, Rebeca, Rodriguez, Antonio, Martinez, Sonia, Oyarzabal, Julen, Pastor, Joaquin, Bischoff, James R., Fernandez-Capetillo, Oscar
Publicado no Nat Struct Mol Biol (2011)

Fragment-Hopping-Based Discovery of a Novel Chemical Series of Proto-Oncogene PIM-1 Kinase Inhibitors

Por Saluste, Gustavo, Albarran, Maria I., Alvarez, Rosa M., Rabal, Obdulia, Ortega, Miguel Angel, Blanco, Carmen, Kurz, Guido, Salgado, Antonio, Pevarello, Paolo, Bischoff, James R., Pastor, Joaquin, Oyarzabal, Julen
Publicado em 2012

The STE20 Kinase HGK Is Broadly Expressed in Human Tumor Cells and Can Modulate Cellular Transformation, Invasion, and Adhesion

Por Wright, Jocelyn H., Wang, Xueyan, Manning, Gerard, LaMere, Brandon J., Le, Phuong, Zhu, Shirley, Khatry, Deepak, Flanagan, Peter M., Buckley, Sharon D., Whyte, David B., Howlett, Anthony R., Bischoff, James R., Lipson, Kenneth E., Jallal, Bahija
Publicado em 2003

Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma

Por Wozniak, Magdalena B., Villuendas, Raquel, Bischoff, James R., Aparicio, Carmen Blanco, Martínez Leal, Juan F., de La Cueva, Paloma, Rodriguez, Ma Elena, Herreros, Beatriz, Martin-Perez, Daniel, Longo, Maria I., Herrera, Marta, Piris, Miguel Á., Ortiz-Romero, Pablo L
Publicado em 2010

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

Por Link, Wolfgang, Oyarzabal, Julen, Serelde, Beatriz G., Albarran, Maria Isabel, Rabal, Obdulia, Cebriá, Antonio, Alfonso, Patricia, Fominaya, Jesus, Renner, Oliver, Peregrina, Sandra, Soilán, David, Ceballos, Plácido A., Hernández, Ana-Isabel, Lorenzo, Milagros, Pevarello, Paolo, Granda, Teresa G., Kurz, Guido, Carnero, Amancio, Bischoff, James R.
Publicado em 2009

Simultaneous inhibition of pan-phosphatidylinositol-3-kinases and MEK as a potential therapeutic strategy in peripheral T-cell lymphomas

Por Martín-Sánchez, Esperanza, Rodríguez-Pinilla, Socorro M., Sánchez-Beato, Margarita, Lombardía, Luis, Domínguez-González, Beatriz, Romero, Diana, Odqvist, Lina, García-Sanz, Pablo, Wozniak, Magdalena B., Kurz, Guido, Blanco-Aparicio, Carmen, Mollejo, Manuela, Alves, F. Javier, Menárguez, Javier, González-Palacios, Fernando, Rodríguez-Peralto, José Luis, Ortiz-Romero, Pablo L., García, Juan F., Bischoff, James R., Piris, Miguel A.
Publicado em 2013

PIM Kinases as Potential Therapeutic Targets in a Subset of Peripheral T Cell Lymphoma Cases

Por Martín-Sánchez, Esperanza, Odqvist, Lina, Rodríguez-Pinilla, Socorro M., Sánchez-Beato, Margarita, Roncador, Giovanna, Domínguez-González, Beatriz, Blanco-Aparicio, Carmen, García Collazo, Ana M., Cantalapiedra, Esther González, Fernández, Joaquín Pastor, del Olmo, Soraya Curiel, Pisonero, Helena, Madureira, Rebeca, Almaraz, Carmen, Mollejo, Manuela, Alves, F. Javier, Menárguez, Javier, González-Palacios, Fernando, Rodríguez-Peralto, José Luis, Ortiz-Romero, Pablo L., Real, Francisco X., García, Juan F., Bischoff, James R., Piris, Miguel A.
Publicado no PLoS One (2014)