Simultaneous inhibition of pan-phosphatidylinositol-3-kinases and MEK as a potential therapeutic strategy in peripheral T-cell lymphomas

Peripheral T-cell lymphomas are very aggressive hematologic malignancies for which there is no targeted therapy. New, rational approaches are necessary to improve the very poor outcome in these patients. Phosphatidylinositol-3-kinase is one of the most important pathways in cell survival and prolife...

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Detalhes bibliográficos
Main Authors: Martín-Sánchez, Esperanza, Rodríguez-Pinilla, Socorro M., Sánchez-Beato, Margarita, Lombardía, Luis, Domínguez-González, Beatriz, Romero, Diana, Odqvist, Lina, García-Sanz, Pablo, Wozniak, Magdalena B., Kurz, Guido, Blanco-Aparicio, Carmen, Mollejo, Manuela, Alves, F. Javier, Menárguez, Javier, González-Palacios, Fernando, Rodríguez-Peralto, José Luis, Ortiz-Romero, Pablo L., García, Juan F., Bischoff, James R., Piris, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533660/
https://ncbi.nlm.nih.gov/pubmed/22801959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.068510
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