An A91V SNP in the Perforin Gene Is Frequently Found in NK/T-Cell Lymphomas

NK/T-cell lymphoma (NKTCL) is the most frequent EBV-related NK/T-cell disease. Its clinical manifestations overlap with those of familial haemophagocytic lymphohistiocytosis (FHLH). Since PERFORIN (PRF1) mutations are present in FHLH, we analysed its role in a series of 12 nasal and 12 extranasal-NK...

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Detaylı Bibliyografya
Asıl Yazarlar: Manso, Rebeca, Rodríguez-Pinilla, Socorro María, Lombardia, Luis, Ruiz de Garibay, Gorka, del Mar López, Maria, Requena, Luis, Sánchez, Lydia, Sánchez-Beato, Margarita, Piris, Miguel Ángel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954696/
https://ncbi.nlm.nih.gov/pubmed/24632576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091521
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