Intrinsic Contribution of Perforin to NK-Cell Homeostasis during Mouse Cytomegalovirus Infection

In addition to their role as effector cells in virus control, natural killer (NK) cells have an immunoregulatory function in shaping the antiviral T-cell response. This function is further pronounced in perforin-deficient mice that show the enhanced NK-cell proliferation and cytokine secretion upon...

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Publicado en:Front Immunol
Autores principales: Arapović, Maja, Brizić, Ilija, Popović, Branka, Jurković, Slaven, Jordan, Stefan, Krmpotić, Astrid, Arapović, Jurica, Jonjić, Stipan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822405/
https://ncbi.nlm.nih.gov/pubmed/27092144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00133
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