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An A91V SNP in the Perforin Gene Is Frequently Found in NK/T-Cell Lymphomas
NK/T-cell lymphoma (NKTCL) is the most frequent EBV-related NK/T-cell disease. Its clinical manifestations overlap with those of familial haemophagocytic lymphohistiocytosis (FHLH). Since PERFORIN (PRF1) mutations are present in FHLH, we analysed its role in a series of 12 nasal and 12 extranasal-NK...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954696/ https://ncbi.nlm.nih.gov/pubmed/24632576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091521 |
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