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VEGF signalling enhances lesion burden in KRIT1 deficient mice

The exact molecular mechanisms underlying CCM pathogenesis remain a complicated and controversial topic. Our previous work illustrated an important VEGF signalling loop in KRIT1 depleted endothelial cells. As VEGF is a major mediator of many vascular pathologies, we asked whether the increased VEGF...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: DiStefano, Peter V., Glading, Angela J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933401/
https://ncbi.nlm.nih.gov/pubmed/31746130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14773
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