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Rap1 and its effector KRIT1/CCM1 regulate β-catenin signaling
KRIT1, also called CCM1, is a member of a multiprotein complex that contains the products of the CCM2 and PDCD10 (also known as CCM3) loci. Heterozygous loss of any of the genes that encode these proteins leads to cerebral cavernous malformations (CCM), which are vascular lesions that are found in a...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Limited
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806902/ https://ncbi.nlm.nih.gov/pubmed/20007487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003293 |
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