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Rap1 and its effector KRIT1/CCM1 regulate β-catenin signaling

KRIT1, also called CCM1, is a member of a multiprotein complex that contains the products of the CCM2 and PDCD10 (also known as CCM3) loci. Heterozygous loss of any of the genes that encode these proteins leads to cerebral cavernous malformations (CCM), which are vascular lesions that are found in a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Glading, Angela J., Ginsberg, Mark H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Limited 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806902/
https://ncbi.nlm.nih.gov/pubmed/20007487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003293
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