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Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling.
The small GTPase Rap1 has been implicated in both negative and positive control of Ras-mediated signalling events. We have investigated which extracellular signals can activate Rap1 and whether this activation leads to a modulation of Ras effector signalling, i.e. the activation of ERK and the small...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170918/ https://ncbi.nlm.nih.gov/pubmed/9774335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.20.5905 |
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