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Specificity in Ras and Rap Signaling

Ras and Rap proteins are closely related small GTPases. Whereas Ras is known for its role in cell proliferation and survival, Rap1 is predominantly involved in cell adhesion and cell junction formation. Ras and Rap are regulated by different sets of guanine nucleotide exchange factors and GTPase-act...

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Detalhes bibliográficos
Main Authors: Raaijmakers, Judith H., Bos, Johannes L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670103/
https://ncbi.nlm.nih.gov/pubmed/19091745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800061200
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