Mechanisms of Isoform Specific Rap2 Signaling during Enterocytic Brush Border Formation

Brush border formation during polarity establishment of intestinal epithelial cells is uniquely governed by the Rap2A GTPase, despite expression of the other highly similar Rap2 isoforms (Rap2B and Rap2C). We investigated the mechanisms of this remarkable specificity and found that Rap2C is spatiall...

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Bibliographic Details
Main Authors: Bruurs, Lucas J. M., Bos, Johannes L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159233/
https://ncbi.nlm.nih.gov/pubmed/25203140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106687
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