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OSTM1 Regulates β-catenin/Lef1 Interaction and is Required for Wnt/β-catenin Signaling

The Wnt/β-catenin signaling pathway controls key aspects of embryonic development and adult tissue homeostasis, including the formation and maintenance of bone. Recently, mutations in the OSTM1 gene were found to be the cause of severe autosomal recessive osteopetrosis in both the mouse and humans....

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Publicado en:Cell Signal
Autores principales: Feigin, Michael E., Malbon, Craig C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275117/
https://ncbi.nlm.nih.gov/pubmed/18296023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.01.009
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