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NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells
Nemo-like kinase (NLK/Nlk) is an evolutionarily conserved protein kinase involved in Wnt/β-catenin signalling. However, the roles of NLK in Wnt/β-catenin signalling in vertebrates remain unclear. Here, we show that inhibition of Nlk2 function in zebrafish results in decreased Lymphoid enhancer facto...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343332/ https://ncbi.nlm.nih.gov/pubmed/22373574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.46 |
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