Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

The c-myb proto-oncogene product (c-Myb) regulates both the proliferation and apoptosis of hematopoietic cells by inducing the transcription of a group of target genes. However, the biologically relevant molecular mechanisms that regulate c-Myb activity remain unclear. Here we report that c-Myb prot...

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Autori principali: Kanei-Ishii, Chie, Ninomiya-Tsuji, Jun, Tanikawa, Jun, Nomura, Teruaki, Ishitani, Tohru, Kishida, Satoshi, Kokura, Kenji, Kurahashi, Toshihiro, Ichikawa-Iwata, Emi, Kim, Yongsok, Matsumoto, Kunihiro, Ishii, Shunsuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC387421/
https://ncbi.nlm.nih.gov/pubmed/15082531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1170604
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