Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma

Metformin, an ancient drug commonly used for treating type II diabetes, has been associated to anti-cancer capacity in a variety of developing cancers, though the mechanism remains elusive. Here, we aimed to examine the inhibitory effect of metformin in osteosarcoma. Herein, we demonstrated that met...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Biol Sci
Prif Awduron: Li, Bo, Zhou, Pingting, Xu, Kehan, Chen, Tianrui, Jiao, Jian, Wei, Haifeng, Yang, Xinghai, Xu, Wei, Wan, Wei, Xiao, Jianru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930379/
https://ncbi.nlm.nih.gov/pubmed/31892847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.33787
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg