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Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation

PURPOSE: Polyphyllin VI, a main active saponin isolated from traditional medicinal plant Paris polyphylla, has exhibited antitumor activities in several cancer cell lines. In the present study, we investigated the antitumor effect of Polyphyllin VI against human osteosarcoma cells (U2OS) and the und...

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書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Yuan, Yong-Liang, Jiang, Neng, Li, Ze-Yun, Song, Zhi-Zhen, Yang, Zhi-Heng, Xue, Wen-Hua, Zhang, Xiao-Jian, Du, Yue
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717844/
https://ncbi.nlm.nih.gov/pubmed/31695327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S194961
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