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Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation

PURPOSE: Polyphyllin VI, a main active saponin isolated from traditional medicinal plant Paris polyphylla, has exhibited antitumor activities in several cancer cell lines. In the present study, we investigated the antitumor effect of Polyphyllin VI against human osteosarcoma cells (U2OS) and the und...

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Enregistré dans:
Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Yuan, Yong-Liang, Jiang, Neng, Li, Ze-Yun, Song, Zhi-Zhen, Yang, Zhi-Heng, Xue, Wen-Hua, Zhang, Xiao-Jian, Du, Yue
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717844/
https://ncbi.nlm.nih.gov/pubmed/31695327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S194961
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