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Acacetin Induces Apoptosis in Human Osteosarcoma Cells by Modulation of ROS/JNK Activation

PURPOSE: The long-term survival rate of osteosarcoma, which is the most common type of primary malignant bone tumor, has stagnated in past decades. Acacetin is a natural flavonoid compound that has antioxidative and anti-inflammatory effects and exhibits extensive therapeutic effects on various canc...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Wang, Shubin, Lin, Binhui, Liu, Wei, Wei, Guojun, Li, Zongguang, Yu, Naichun, Xue, Xiang, Ji, Guangrong
Format: Artigo
Language:Inglês
Published: Dove 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680676/
https://ncbi.nlm.nih.gov/pubmed/33239866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S275148
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