Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma

BACKGROUND: Polyphyllin VI (PPVI), a bioactive component derived from a traditional Chinese herb Paris polyphylla, exhibits potential antitumor activity against hepatocellular carcinoma, as well as breast and lung cancers. However, its effect on glioma remains unknown. METHODS: Five glioma cell line...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Liu, Wei, Chai, Yi, Hu, Libo, Wang, Junhua, Pan, Xin, Yuan, Hongyu, Zhao, Zitong, Song, Yongmei, Zhang, Yuqi
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078907/
https://ncbi.nlm.nih.gov/pubmed/32214827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S243953
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