Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation

BACKGROUND: Glioblastoma multiforme (GBM) is the most aggressive of the primary brain tumors, with a grim prognosis despite intensive treatment. In the past decades, progress in research has not significantly increased overall survival rate. METHODS: The in vitro antineoplastic effect and mechanism...

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Detalhes bibliográficos
Main Authors: Trejo-Solís, Cristina, Jimenez-Farfan, Dolores, Rodriguez-Enriquez, Sara, Fernandez-Valverde, Francisca, Cruz-Salgado, Arturo, Ruiz-Azuara, Lena, Sotelo, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404907/
https://ncbi.nlm.nih.gov/pubmed/22540380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-156
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