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Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo

Erianin, a natural product derived from Dendrobium chrysotoxum, has exhibited potential antitumor activity in various malignancies, including hepatocarcinoma, melanoma, and promyelocytic leukemia. Here we explored the effects of erianin on osteosarcoma (OS) in vitro and in vivo and further elucidate...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, H, Zhang, T, Sun, W, Wang, Z, Zuo, D, Zhou, Z, Li, S, Xu, J, Yin, F, Hua, Y, Cai, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143374/
https://ncbi.nlm.nih.gov/pubmed/27253411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.138
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